基本信息：

杨源，理学博士，教授，硕士生导师，湖湘青年英才（荷尖），湖南省优青，长沙市杰青。2011年6月和2014年6月在威尼斯432888cam获得学士和硕士学位（导师：梁云教授），2018年6月毕业于湖南大学获理学博士学位，师从李金恒教授（国家杰出青年科学基金获得者）。2018年7月加入威尼斯432888cam，校聘副教授，硕士生导师。2019年入选学校世承人才计划"青年优秀人才"。2020年12月晋升副教授。近年来致力于开发高效、原子和步骤经济性的合成方法，主要聚焦于钯催化串联C-H官能团化反应研究，在基于环钯物种的转化反应、C-H活化/硅基化反应、C-H活化/脱羧环化反应等领域取得了一系列研究成果。目前共发表SCI学术论文50余篇，其中以通讯/第一作者身份在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Sci.、Org. Lett.、Org. Chem. Front.、Chem. Commun.、J. Org. Chem.等期刊上发表SCI学术论文30余篇。主持国家自然科学基金面上/青年项目、湖南省自然科学基金优秀青年项目、长沙市杰出创新青年项目等项目8项。

联系信息：

E-mail：yuanyang@hunnu.edu.cn; yangyuan071@126.com

手机：18173114835

课题组主页：https://www.x-mol.com/groups/yang_yuan

研究领域：

钯催化串联C-H官能团化反应：

1. 基于环钯物种的转化反应

2. C-H活化/硅基化反应

3. C-H活化/脱羧环化反应

招生计划：
研究生招生方向为有机化学，每年硕士招生指标2-3名，欢迎能吃苦耐劳、积极向上、善于思考、热衷于科研的学生加入课题组。

主持科研项目：

2. 国家自然科学基金青年项目（2020.01-2022.12）

3. 湖南省自然科学基金优秀青年项目（2023.01-2025.12）

4. 湖南省自然科学基金青年项目（2020.01-2022.12）

5. 长沙市杰出创新青年项目（2023.01-2025.12）

6. 湖南省教育厅重点项目（2022.10-2025.09）

7. 湖南省教育厅优秀青年项目（2019.10-2022.09）

8. 威尼斯432888cam特聘副教授人才引进基金（2018.07-2023.06）

代表性论文：

1. Liwei Zhou,§ Xiahong Chen,§ Qiong Peng,§ Zhiwei Li, Shujia Qiao, Guobo Deng, Yun Liang,* Ming Lei,* and Yuan Yang*, A Cascade C(sp3)−H Annulation Involving C(alkyl),C(alkyl)-Palladacycle Intermediates, Angew. Chem. Int. Ed. 2024, 63, e202412336. (§co-first author)
   

2. Yankun Xu,† Mingjie Sun,† Weiwei Xu, Guobo Deng, Yun Liang,* and Yuan Yang*, Versatile Tetrasilane for Time-Controlled Palladium-Catalyzed Divergent Synthc via C−H Activation, J. Am. Chem. Soc. 2023, 145, 15303-15312. (†co-first author)
   

3. Yuan Yang, Ren-Jie Song*, Xuan-Hui Ouyang, Cheng-Yong Wang, Jin-Heng Li*, Shenglian Luo*, Iron-Catalyzed Intermolecular 1,2-Difunctionalization of Styrenes and Conjugated Alkenes with Silanes and Nucleophiles, Angew. Chem. Int. Ed. 2017, 56, 7916-7919.

4. Yuan Yang, Ming-Bo Zhou, Xuan-Hui Ouyang, Rui Pi, Ren-Jie Song, Jin-Heng Li*, Rhodium(III)-Catalyzed [3+2]/[5+2] Annulation of 4-Aryl 1,2,3-Triazoles with Internal Alkynes through Dual C(sp2)-H Functionalization, Angew. Chem. Int. Ed. 2015, 54, 6595-6599.

5. Yankun Xu, Weiwei Xu, Xinyang Chen, Xiai Luo, Haiyan Lu, Minghao Zhang, Xiumei Yang, Guobo Deng, Yun Liang*, Yuan Yang*, Me3SiSiMe2(OnBu): a disilane reagent for the synthesis of diverse silacycles via Brook- and retro-Brook-type rearrangement, Chem. Sci. 2021,12, 11756-11761.

6. Bing Liu,§ Sen Lei,§ Zhendong Cheng, Liwei Zhou*, Guobo Deng, Yun Liang, and Yuan Yang*, Palladium-Catalyzed Bicycloaromatization of o-(Alkynyl)styrenes with Alkynes: Economical Access to Chrysene Derivatives, Org. Lett. 2024, 26, 8509–8514. (§co-first author)

7. Liwei Zhou,*,§ Pengyang Jing,§ Zhiwei Li, Rui Liu, Jiannan Chen, Guobo Deng, Yun Liang,* and Yuan Yang*, Norbornene Derivatives-Controlled Palladium-Catalyzed Divergent Synthesis of Dibenzo[a,c]cycloheptenones and Fluorenones from Aryl Iodides and α‑Oxocarboxylic Acids, Org. Lett. 2024, 26, 676-680. (§co-first author)

8. Xiahong Chen, Yan Chen, Weiwei Xu, Guobo Deng, Yun Liang*, Yuan Yang*, Pd(II)-Catalyzed Synthesis of Polycyclic Heteroarenes via an Aminopalladation/C−H Activation/Dealkylation/Decarboxylative Cyclization Cascade, Org. Lett. 2022, 24, 7282-7287.

9. Fengru Zhou,† Liwei Zhou,† Pengyang Jing, Mingjie Sun, Guobo Deng, Yun Liang,* Yuan Yang*, Chemoselective Transformations of Cyclic β‑Bromoacrylic Acids with Palladacycles Formed by Aryl Iodides to Access Fused or SpiroPolycycles, Org. Lett. 2022, 24, 1400-1404. (†co-first author) (Highlighted by CBG，今日论文)

10. Liwei Zhou, Mingjie Sun, Fengru Zhou, Guobo Deng, Yuan Yang*, Yun Liang*, Atmosphere-Controlled Palladium-Catalyzed Divergent Decarboxylative Cyclization of 2‑Iodobiphenyls and α‑Oxocarboxylic Acids, Org. Lett. 2021, 23, 7150-7155. (Highlighted by CBG)

11. Minghao Zhang, Wenbo Deng, Mingjie Sun, Liwei Zhou, Guobo Deng, Yun Liang, Yuan Yang*, α‑Bromoacrylic Acids as C1 Insertion Units for Palladium-Catalyzed Decarboxylative Synthesis of Diverse Dibenzofulvenes, Org. Lett. 2021, 23, 5744-5749. (Highlighted by CBG)

12. Liwei Zhou, Shujia Qiao, Fengru Zhou, Xinyu Xuchen, Guobo Deng, Yuan Yang*,Yun Liang*, α‑Oxocarboxylic Acids as Three-Carbon Insertion Units for Palladium-Catalyzed Decarboxylative Cascade Synthesis of Diverse Fused Heteropolycycles, Org. Lett. 2021, 23, 2878-2883. (Highlighted by CBG)

13. Xiumei Yang, Xiahong Chen, Yankun Xu, Minghao Zhang, Guobo Deng, Yuan Yang*, Yun Liang*, Palladium-Catalyzed [4 + 3] or [2 + 2 + 3] Annulation via C-H Activation and Subsequent Decarboxylation: Access to Heptagon-Embedded Polycyclic Aromatic Hydrocarbons, Org. Lett. 2021, 23, 2610-2615.

14. Xiai Luo, Liwei Zhou, Haiyan Lu, Guobo Deng, Yun Liang*, Chunming Yang*, Yuan Yang*, Palladium-Catalyzed Domino Heck/C-H Activation/Decarboxylation: A Rapid Entry to Fused Isoquinolinediones and Isoquinolinones, Org. Lett. 2019, 21, 9960-9964.

15. Wenguang Li, Wenqi Chen, Bang Zhou, Yankun Xu, Guobo Deng, Yun Liang*, Yuan Yang*, NBE-Controlled Palladium-Catalyzed Interannular Selective C-H Silylation: Access to Divergent Silicon-Containing 1,1′-Biaryl-2-Acetamides, Org. Lett. 2019, 21, 2718−2722.

16. Xiumei Yang, Haiyan Lu, Xiaoming Zhu, Liwei Zhou, Guobo Deng, Yuan Yang*, Yun Liang*, Palladium-Catalyzed Cascade Cyclization of Alkene-Tethered Aryl Halides with o-Bromobenzoic Acids: Access to Diverse Fused Indolo[2,1-a]isoquinolines, Org. Lett. 2019, 21, 7284-7288.

17. Yuzhong Yang, Bang Zhou, Xiaoming Zhu, Guobo Deng, Yun Liang*, Yuan Yang*, Palladium-Catalyzed Synthesis of Triphenylenes via Sequential C-H Activation and Decarboxylation, Org. Lett. 2018, 20, 5402-5405.

18. Liang Chen(#), Hao Min(#), Weilan Zeng, Xiaoming Zhu, Yun Liang*, Guobo Deng*, Yuan Yang*, Transition-Metal-Free Sulfuration/Annulation of Alkenes: Economical Access to Thiophenes Enabled by the Cleavage of Multiple C-H Bonds, Org. Lett. 2018, 20, 7392-7395.

19. Yuan Yang, Jiang-Xi Yu, Xuan-Hui Ouyang, Jin-Heng Li*, Complex Annulations through Silver Carbenoid Intermediate: An Alternative Entry to Transformations of 1,2,3-Triazoles, Org. Lett. 2017,19, 3982-3985.

20. Xiahong Chen, Sen Lei, Yan Chen, Wenbo Deng, Guobo Deng*, Yun Liang*, Yuan Yang*, Decarboxylative cyclization of o-chlorobenzoic acids with C,C-palladacycles formed by an aminopalladation/dealkylation strategy to access dibenzo[a,c]carbazoles, Org. Chem. Front. 2022, 9, 3414-3419.

21. Minghao Zhang, Fengru Zhou, Xinyu Xuchen, Liwei Zhou, Guobo Deng, Yun Liang, Yuan Yang*, A palladium-catalyzed Heck/[4 + 1] decarboxylative cyclization cascade to access diverse heteropolycycles by using α-bromoacrylic acids as C1 insertion units, Org. Chem. Front. 2021, 8, 5687-5692.

22. Liwei Zhou, Xiaodong Liu, Haiyan Lu, Guobo Deng, Yun Liang*, Yuan Yang*, Jin-Heng Li*, Copper-catalyzed [3 + 2]/[3 + 2] carboannulation of dienynes and arylsulfonyl chlorides enabled by Smiles rearrangement: access to cyclopenta[a]indene-fused quinolinones, Org. Chem. Front. 2021, 8, 5092-5097.

23. Mingjie Sun, Xinyang Chen, Zichao Feng, Guobo Deng, Yuan Yang*, Yun Liang*, A Catellani and retro-Diels-Alder strategy to access 1-amino phenanthrenes via ortho- and interannular C-H activation of 2-iodobiphenyls, Org. Chem. Front. 2021, 8, 6535-6540.

24. Wenguang Li, Chao Zhang, Haiyan Lu, Yajun Wang, Guobo Deng, Yun Liang*, Yuan Yang*, Pd-Catalyzed one-pot synthesis of vinylsilanes via a three-component tandem reaction.Org. Chem. Front. 2020, 7, 2075-2081.

25. Haiyan Lu, Xiumei Yang, Liwei Zhou, Wenguang Li, Guobo Deng, Yuan Yang*,  Yun Liang*, Palladium-catalyzed domino Heck-disilylation and -borylation of alkene-tethered 2-(2-halophenyl)-1H-indoles: access to diverse disilylated and borylated indolo[2,1-a]isoquinolines, Org. Chem. Front. 2020, 7,  2016-2021.

26. Yuan Yang, Chong-Hui Xu, Zhi-Qiang Xiong, Jin-Heng Li*, Visible light photoredox alkylazidation of alkenes with sodium azide and heteroarenium salts: entry to azido-containing 1,4-dihydropyridines, Chem. Commun. 2020, 56, 9549-9552.

27. Yuan Yang, Ren-Jie Song*, Yang Li, Xuan-Hui Ouyang, Jin-Heng Li*, De-Liang He*, Oxidative Radical Divergent Si-Incorporation: Facile Access to Si-Containing Heterocycles, Chem. Commun. 2018, 54, 1441-1444.

28. Yankun Xu, Xiaodong Liu, Wenqi Chen, Guobo Deng, Yun Liang*, Yuan Yang*, Palladium/Norbornene Chemistry: Synthesis of Norbornene-Containing Arylsilanes Involving Double C-Si Bond Formation, J. Org. Chem. 2018, 83, 13930-13939.

29. Xiai Luo, Wenguang Li, Haiyan Lu, Guobo Deng, Yuan Yang*, Chunming Yang*, Yun Liang*, Palladium-catalyzed cascade synthesis of spirocyclic oxindoles via regioselective C2-H arylation and C8-H alkylation of naphthalene ring, Chin. Chem. Lett. 2021, 32, 713-716.

30. Yuan Yang, Chong-Hui Xu, Fan Teng, Jin-Heng Li*, Dearomatization-Enabled Visible-Light-Induced 1,2-Alkylsulfonylation of Alkenes Using Sodium Sulfinates and Pyridinium Salts, Adv. Synth. Catal. 2020, 362, 3369-3373.